|Instituto Butantan is a Brazilian biomedical research center affiliated to the São Paulo State Secretary of Health. It is located near the campus of the University of São Paulo, in the city of the same name.|
The Institute was founded by the Brazilian physician and biomedical scientist Vital Brazil in 1901, according to Pasteur Institute paradigm. It is internationally renowned for its research on venomous animals. It maintains one of largest collections of serpents in the world, comprising ca. 54,000 specimens, and it is also a state-supported producer of vaccines against many infectious diseases, such as rabies, hepatitis, botulism, tetanus, diphtheria, pertussis and tuberculosis, as well as polyvalent and monovalent antivenoms against the bites of snakes, lizards, bees, scorpions and spiders (which, historically were first developed in the beginning of the 20th century by Dr. Vital Brazil and his coworkers).