On January 18, 1943, the first instance of armed resistance occurred when the Germans started the final expulsion of the remaining Jews. The Jewish fighters had some success: the expulsion stopped after four days and the ŻOB and ŻZW resistance organizations took control of the Ghetto, building shelters and fighting posts and operating against Jewish collaborators.
The final battle started on the eve of Passover of April 19, 1943, when a Nazi force consisting of several thousand troops entered the ghetto. After initial setbacks, the Germans under the field command of Jürgen Stroop systematically burned and blew up the ghetto buildings, block by block, rounding up or murdering anybody they could capture. Significant resistance ended on April 23, and the Nazi operation officially ended in mid-May, symbolically culminated with the demolition of the Great Synagogue of Warsaw on May 16. According to the official report, at least 56,065 people were killed on the spot or deported to German Nazi concentration and death camps, most of them to Treblinka.